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中国防痨杂志 ›› 2014, Vol. 36 ›› Issue (12): 1015-1020.doi: 10.3969/j.issn.1000-6621.2014.12.004

• 论著 • 上一篇    下一篇

全国14岁以下儿童肺结核疫情特征分析

刘二勇 马艳 李涛 杜昕 周林 成诗明   

  1. 102206 北京,中国疾病预防控制中心结核病预防控制中心(刘二勇、李涛、杜昕、周林、成诗明);中国疾病预防控制中心结核病防治临床中心办公室(马艳)
  • 收稿日期:2014-11-02 出版日期:2014-12-10 发布日期:2015-02-28
  • 通信作者: 周林;成诗明 E-mail:zhoulin@chinatb.org; smcheng@chinatb.org
  • 基金资助:

    全球基金结核病控制策略研究(TB 12-011)

Analysis on national pulmonary tuberculosis epidemic characteristics of children under 14 years old

LIU Er-yong, MA Yan, LI Tao, DU Xin, ZHOU Lin, CHENG Shi-ming   

  1. National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206China
  • Received:2014-11-02 Online:2014-12-10 Published:2015-02-28
  • Contact: ZHOU Lin;CHENG Shi-ming E-mail:zhoulin@chinatb.org; smcheng@chinatb.org

摘要: 目的 分析全国14岁以下儿童肺结核疫情特征与变化趋势,为国家儿童结核病控制策略的制定提供依据。 方法 利用1979、1990、2000年全国结核病流行病学抽样调查(简称“流调”)资料中儿童Mtb感染和结核病患儿相关资料,分析全国儿童Mtb感染率和患病率;对2001—2010年全国肺结核报告发病资料进行统计,分析儿童肺结核报告发病率变化特征。结果 1979年流调全国0~14岁儿童Mtb感染率为8.8%,肺结核患病率为247.1/10万,涂阳患病率为7.5/10万;2000年分别为9.0%、91.8/10万和6.7/10万。2001—2010年,全国0~14岁儿童肺结核报告发病率由2001年的9.3/10万(26 563/284 520 000)降至2010年的4.0/10万(9751/246 550 000)。儿童不同年龄组肺结核报告发病率中,2001年以0~4岁年龄组最高,为11.6/10万(7995/68 970 000);2010年10~14岁年龄组最高,为7.3/10万(5932/81 630 000)。儿童肺结核报告发病例数占全人群肺结核报告发病例数的比例逐年下降,由2001年4.7%(26 563/570 527)降为2010年1.0%(9751/991 350)。结论 全国儿童Mtb感染率无下降,活动性结核病患病率和涂阳患病率快速下降;儿童肺结核报告发病率呈下降趋势。

关键词: 结核, 肺/流行病学, 患病率, 儿童

Abstract: Objective To analyze the national characteristics and change trend of tuberculosis in children under the age of 14, provide the basis for children’s TB control strategies.  Methods We obtained the TB infection rate and the prevalence rate from the 1979, 1990 and 2000 national epidemiological sampling survey of tuberculosis. We also used pulmonary TB incidence data from 2001 to 2010 to analyze the trend of childhood TB incidence.  Results In 1979, the tuberculosis infection rate in children under 14 years old is 8.8%, and tuberculosis prevalence rate was 247.1/100 000, smear positive prevalence rate was 7.5/100 000. In 2000, these rates are 9.0%, 91.8/100 000 and 6.7/100 000 respectively. The national average children reported incidence of tuberculosis decreased from 9.3/100 000 (26 563/284 520 000)in 2001 to 4.0/100 000(9751/246 550 000) in 2010. In different age groups of children, in 2001, the 0-4 year old group was highest of 11.6/100 000(7995/68 970 000). In 2010 the 10-14 year age group was highest to 7.3/100 000(5932/81 630 000). The percentage of reported incidence cases of childhood pulmonary tuberculosis in tuberculosis cases among total population declined by year from 4.7%(26 563/570 527) in 2001 to 1.0%(9751/991 350) in 2010. Conclusion There has no decline in the children Mycobacterium tuberculosis infection rate nationwide; the prevalence of active tuberculosis and smear positive cases decreased rapidly; the reported incidence of childhood tuberculosis showed the decreasing trend.

Key words: Tuberculosis, pulmonary/epidemiology, Prevalence, Child